UAMS.EDU

Graduate Gene Expression

REGULATION OF PROKARYOTIC & EUKARYOTIC

Fall 2013 – GENE EXPRESSION (5143)

Rayford Auditorium Room 106-2

Biomedical Research Center II

Tuesdays & Thursdays

9:00 am – 11:00 am

Course Director: Patricia Wight

Slides and Readings are located Here

DATE

LECTURE

INSTRUCTOR

Tue,    08/20/13

Prokaryotic Genome   Organization

Mark Smeltzer
Thurs, 08/22/13

Operons

Mark Smeltzer
Tue,    08/27/13

Prokaryotic transcription

Chia Lee
Thurs, 08/29/13

Regulation of   prokaryotic transcription

Chia Lee
Tue,    09/03/13

Prokaryotic   replication, repair and recombination

Kevin Raney
Thurs, 09/05/13

Eukaryotic Genome   Organization

Helen Benes
Tue,    09/10/13

EXAM 1 (8:30 – 11:30 AM)

Includes   lectures from 8/20/13 – 9/03/13

 
Thurs, 09/12/13

Eukaryotic replication   and repair

Kevin Raney
Tue,    09/17/13

Eukaryotic replication   and repair

Kevin Raney
Thurs, 09/19/13

Eukaryotic   Transcription

Patricia Wight
Tue,    09/24/13

Eukaryotic   Transcription

Patricia Wight
Thurs, 09/26/13

Eukaryotic   Transcription

Patricia Wight
Tue,    10/01/13

Eukaryotic   Transcription

Patricia Wight
Thurs, 10/03/13

Eukaryotic Gene   Regulation

Helen Benes
Tue,    10/08/13

EXAM 2 (8:30 – 11:30 AM)

Includes   lectures from 9/05/13 – 10/03/13

 
Thurs, 10/10/13

Meiosis and Mitosis

Wayne Wahls
Tue,    10/15/13

Meiosis and Mitosis

Wayne Wahls
Thurs, 10/17/13

CAREER DAY

 
Tue,    10/22/13

Genetic Recombination

Wayne Wahls
Thurs, 10/24/13

Posttranscriptional   processing

Xuming Zhang
Tue,    10/29/13

RNA splicing

Xuming Zhang
Thurs, 10/31/13

RNA splicing

Xuming Zhang
Tue,    11/05/13

Reverse transcription

Xuming Zhang
Thurs, 11/07/13

EXAM 3 (8:30 – 11:30 AM)

Includes   lectures from 10/10/13 – 11/05/13

 
Tue,    11/12/13

Prokaryotic & Regulation of Prokaryotic Translation

Angus MacNicol
Thurs, 11/14/13

Eukaryotic translation

Angus MacNicol
Tue,    11/19/13

Regulation of Eukaryotic   translation

Angus MacNicol
Thurs, 11/21/13

Eukaryotic   Differentiation & Development

Mari Davidson
Tue,    11/26/13

Eukaryotic   Differentiation & Development

Mari Davidson
 

THANKSGIVING DAY HOLIDAY

 
Tue,     12/03/13

EXAM 4 (8:30 – 11:30 AM)

Includes lectures from 11/12/13 – 11/26/13

 

 

Prerequisites

It is recommended that students have taken an undergraduate course in biochemistry and/or molecular biology.

Objectives

The goal of this course is for students to acquire a working knowledge of the various methods by which gene expression can be controlled.  A side-by-side comparison of these mechanisms for both prokaryotes and eukaryotes will be explored.  It is anticipated that at the end of this course, students will become proficient at reading the primary literature relevant to gene expression.

Course Structure

The course is 3 credit hours which meet twice a week for 2 hours per session.  The course will be conducted by didactic lectures, as well as, class discussion of current reviews and primary papers.  The students will be assigned a grade solely based on exams, which will be in the format of short answer/essay questions.  Grades will scaled, with the class average typically set at a B. Plus/minus grades will be given in the course, but please note that the graduate school records only solid grades (no +/-).

Reading Material

Readings will mainly consist of recent reviews and primary articles as assigned by the individual Instructors.  Lewin’s Genes XI is recommended as a text for general background.  A copy of the text has been placed on Reserve in the main library (2 hour intervals).

Course Evaluation

The course will be evaluated by the students as per standard UAMS procedures.  Each Instructor will also be evaluated by the students.