Herschel Conaway, Ph.D.

Herschel Conaway, Ph.D.

Associate Professor
Ph.D., University of Missouri
Office:(501) 686-5125
Fax: (501) 686-8167


Dr. Conaway came to UAMS in 1971. He has been employed half-time since July, 2016.

Beginning with a research study published in Biochemical Pharmacology in 1966, Dr. Conaway has published research manuscripts in the medical literature for over 50 years. Dr. Conaway’s research is currently directed at defining physiological agents which stimulate osteoclasts and bone resorption. Recent studies have included a strong collaborative effort with colleagues in Sweden, specifically Professor Ulf H. Lerner, former head, Department of Oral Cell Biology, and Dean of the Dental School, University of Umeå, Umeå, Sweden.

Dr. Conaway taught in the Medical Physiology Course in the Department of Physiology and Biophysics at UAMS for 42 years. During that time, he received three “Golden Apple Awards” from M1 medical classes designating him as an outstanding instructor. In the new UAMS medical school curriculum instituted in 2013, Dr. Conaway has been serving as the Director of the Endocrine/Reproduction Module taught in the M2 year. Dr. Conaway has also directed and been teaching an M4 medical student Endocrine Elective for the past 40 years.  For his teaching at UAMS, Dr. Conaway has been presented “Red Sash” awards of recognition on nine occasions from graduating senior classes. In addition, he has served as the Course Coordinator and taught in the Graduate School Course, Cellular Endocrinology, in the Graduate School Course, General Physiology, and in the Graduate School Course, Advanced Physiology.

Dr. Conaway’s teaching career at UAMS has also included directing and teaching a Graduate Physiology Course in the Nursing School for four years when the Master of Science degree in the Nursing School was established, as well as teaching a Physiology Course with a colleague in the School of Pharmacy for one year.

On two occasions, Dr. Conaway has served as an elected representative from the College of Medicine to the Academic Senate Council. Dr. Conaway has been the Director of Graduate Studies in the Department of Physiology and Biophysics. He also has served on the campus-wide Graduate School Committee and on the Graduate Student Research Funds Allocation Committee. In addition, Dr. Conaway has served on Medical School Promotions Committees, as a member of the Research Council, in the Physician Educator Honors Program, as Chairman of the Animal Care and Use Committee at UAMS and as the Department of Physiology and Biophysics Representative on the Medical School Curriculum Committee.


Representative Publications

Conaway HH, Henning P, Lie A, Tuckermann J, Lerner UH. Activation of dimeric glucocorticoid receptors in osteoclast progenitors. Bone, 92: 43-54, 2016.

Henning P, Conaway HH, Lerner UH.  Retinoid receptors in bone and their role in bone remodeling. Frontiers in Endocrinology 6: 1-13, 2015

Conaway HH, Henning, P, Lerner UH. Vitamin A metabolism, action, and role in skeletal homeostasis.  Endocr Rev, 34: 766-797, 2013.

Souza PPC, Palmquist P, Lundberg P, Lundgren I, Hanstrom L, Souza  JAC, Conaway HH, Lerner UH. Interleukin-4 and interleukin-13 inhibit the expression of leukemia inhibitory factor and interleukin-11 in fibroblasts. Mol Immunol, 49: 601-610, 2012.

Conaway HH, Pirhayati A, Persson E, Svensson O, Lindholm C, Henning P, Tuckerman J, Lerner UH. Retinoids stimulate periosteal bone resorption by enhancing RANKL, a response inhibited by monomeric glucocorticoid receptor. J Biol Chem  286:31425-31436, 2011.

Conaway HH, Persson E, Hahlen M, Granholm S, Svensson O, Pettersson U, Lie A, Lerner UH. Retinoids inhibit differentiation of hematopoetic osteoclast precursors. FASEB J. 23: 3526-3538, 2009.

Swanson C, Lorentzon M, Conaway HH, Lerner UH. Glucocorticoid regulation of osteoclast differentiation and expression of receptor activator of nuclear factor-kB (NF-kB) ligand, osteoprotegerin, and receptor activator of NF-kB in mouse calvarial bones. Endocrinology 147:3613-3622, 2006.

Palmquist P, Lundberg P, Persson E, Anders J, Lundgren I, Lie A, Conaway HH, Lerner UH.   Inhibition of hormone and cytokine stimulated osteoclastogenesis and bone resorption by interleukin-4 and interleukin-13 is associated with increased OPG and decreased RANKL and RANK in a STAT6 dependent pathway. J Biol Chem 281:2414-2429, 2006

Schwab AM, Granholm S, Persson E, Wilkes B, Lerner UH, Conaway HH. Stimulation of resorption in cultured mouse calvarial bones by thiazolidinediones. Endocrinology 146:4349-4361, 2005.


Link to Dr. Conaway at PubMed